Endocrine Abstracts

Introduction: Teratomas are complex malformative tumors defined by the presence of tissues derived from the 3 embryonic layers. They can be mature or immature, depending on their degree of differentiation. They are most often found in the sacrococcygeal region and the gonads. Cervical location is exceptional (4%).Observation: We report the case of a 45-year-old patient who presented with a right cervical swelling that progressively increased in volume. T...

Introduction: The occurrence of thyroid cancer in Basedow disease is rare. We report a series of five cases of patients with Basedow disease who were operated on and whose pathological examination showed an association with differentiated thyroid cancer.Clinical cases: We report a series of five patients with a mean age of 39 years. The diagnosis of Basedow disease was made on the basis of clinical, biological and scintigraphic evidence. Cervical ultraso...

Introduction: The cystic nodule is an unusual presentation of papillary thyroid carcinoma (PTC), seen in less than 10% of cases. Ultrasound discovery of a thyroid cyst represents less than 5% risk of malignancy. We report the case of a patient followed for papillary thyroid carcinoma in its cystic form.Observation: A 42-year-old patient with no specific history. The patient underwent a right isthmolobectomy for a thyroid nodule. Anatomopathological exami...

Introduction: Liver dysfunction during hyperthyroidism may be secondary to thyrotoxicosis, to an associated liver pathology, or to the medical treatment of hyperthyroidism posing a problem of etiological diagnosis. In this context, we report a demonstrative observation.Case presentation: We report the observation of a 23-year-old female patient, followed for Basedow disease under carbimazole since 1 year, not controlled under medical treatment. During he...

Introduction: Most pituitary adenomas are benign. However, there are invasive forms with rapid growth rate and particular histological signs (atypical adenomas), making them considered pituitary carcinomas without metastases.Observation: A 63-year-old patient was followed for 10 years for Cushing’s disease in the pituitary macrodenoma. Clinical evaluation found Cushing syndrome, pituitary tumor syndrome associated with diplopia, and trigeminal neura...

Introduction: Epstein-Barr virus (EBV) is a well-known human tumor virus with a very high prevalence in the population, this virus is associated with epithelial and lymphoid malignancies, including lymphoepithelioma carcinoma of thyroid. This subtype of thyroid carcinoma is characterized by histologic features similar to those of undifferentiated carcinoma of the thyroid. Case Report: A 17-year-old male patient, his medical and family histories were non-...

Introduction: Neurofibromatosis type 1(NF1) is an autosomal dominant genodermatosis that affect multiple organs. It represents one of the most frequent genetic diseases. The diagnosis is primarily clinical and is based on the NIH criteria (National Institutes of Health) established in 1988, and revised in 2021. We report a case of male patient with NF1 revealed by a pheochromocytoma.Case Report: A 26-years-old man patient with no previous medical history...

Introduction: Partial 21-hydroxylase deficiency is a genetic autosomal recessive disorder responsible for accumulation of the precursor upstream of the enzyme block, 17-hydroxyprogesterone (17OHP), and excessive androgen production.Observation: A 29-year-old woman consulted for hirsutism with a Ferriman–Gallwey score of 25. There were no signs of Cushing syndrome and no abnormalities of sexual development. The Laboratory results revealed testosteron...

Introduction: Pheochromocytoma is a rare neuroendocrine tumor. It is usually diagnosed in subjects between 40 and 50 years of age. The occurrence of pheochromocytoma in the elderly is much rarer and has its own particularities. We report the case of a 70-year-old female patient with invasive pheochromocytoma.Case presentation: A 70-year-old female patient with a history type 2 diabetes for 18 years on oral antidiabetics and insulin. The history of his di...

Introduction: Hypercalcemia is often observed in patients with cancer, secondary to the production s of parathyroid hormone (PTH)-related peptides. However, the association of primary hyperparathyroidism (pHPT) and colon cancer is rarely reported.Case: We present the case of a 76 years old female patient, who was operated one year ago of for a low-grade colorectal adenocarcinoma. As part of her routine workup of her disease she underwent a phosphocalcic ...